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Writer: 

BAYAT HASSAN

Issue Info: 
  • Year: 

    2014
  • Volume: 

    12
Measures: 
  • Views: 

    190
  • Downloads: 

    63
Keywords: 
Abstract: 

VALIDATION: BEFORE USING A NEW METHOD TO ASSAY PATIENT’S SAMPLES, THE METHOD MUST BE VALIDATED; MEANING THAT THE METHOD’S PERFORMANCE MUST BE EVALUATED TO GET SURE THE METHOD COULD ADDRESS THE CLINICALLY NEEDEDQUALITY STANDARDS.PERFORMANCE SPECIFICATIONS TO BE VALIDATED INCLUDE: - LINEARITY/UPPER LIMIT OF THE ASSAY, -VARIATION, -…

Yearly Impact:   مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Writer: 

مرندی وحید

Issue Info: 
  • Year: 

    1384
  • Volume: 

    6
Measures: 
  • Views: 

    376
  • Downloads: 

    0
Abstract: 

چندی است استقرار نظام مدیریت کیفیت و استفاده از ابزارهای متنوع آن در کشور، به شدت مورد توجه واقع شده است. با تدوین و تصویب استاندارد ملی ایران - ایزو سری 9000 ، الزامات استقرار این نظام درسال 1380 به طور رسمی در اختیار مجامع علمی و تخصصی کشور قرار گرفت، هر چند قدمت این استاندارد در دنیا به دهه گذشته آن بازگشته و متن اصلی استاندارد مزبور و ویرایش های جدید آن، مورد استفاده مجامع داخلی قرار داشته است .در این استانداردها، پیش شرط ها و الزامات متعددی برای استقرار نظام مدیریت کیفیت در قالب تعاریفی ارایه شده است. هر چند برخی معادل های پارسی برگزیده برای عملیات با تعریف ارایه شده از آن، از هم خوانی لازم با معانی مورد نظر برخو ردار است اما مطالعه، بررسی و ا مدقه در خصوص نحوه انجام این عملیات با برخی معادل های پیشنهادی، حاکی از عدم تطابق یا عدم دقت در انتخاب واژه معادل می باشد که موجب اختلاف در تعبیر یا استفاده ناهماهنگ متخصصین از یک واژه شده و چه بسا از استفاده معادل پیشنهادی صرف نظر گردیده و همان واژه لاتین، مقبولیت یافته است. یکی از مهم ترین این موارد، واژه Validation می باشد که در استانداردهای مزبور، کلمه صحه گذاری معادل یابی شده است. در این نوشتار، پس از ذکر تاریخچه این لغت و نحوه معرفی آن به حوزه مدیریت کیفیت، برای ارایه تصویر روشنی از نحوه انجام عملیات Validation از رویکرد فرآیندی (Systematic approach) استفاده شده است که مبتنی بر تجارب عملی نگارنده در خصوص این عملیات می باشد. از این رو، با تمسک به تعاریف مراجع معتبر و موشکافی موارد مهم آن، اهداف و قابلیت های این عملیات که فراتر از تنها یک تعریف بوده، به عنوان یک تخصص اساسی دارای سرفصل های آموزشی و دانشگاهی خاص خود می باشد، مورد بحث و بررسی قرار گرفته است. سپس جایگاه ارزیابی در این عملیات و نحوه اجرای آن، به همراه مدل انجام فرآیند Validation معرفی شده و مساله ارزیابی خطر در تعیین اهداف آن مورد ارزیابی قرار گرفته است. استفاده از این رویکرد نشان داده است که هرچند کلمه صحه گذاری (یا دیگر معادل های موجود)، تا حدودی بیانگر فرآیند Validation به عنوان یکی از ارکان استقرار نظام مدیریت کیفیت می باشد اما با این معادل به هیچ وجه از جامعیت لازم برخوردار Validation توجه به اهداف، قابلیت ها و روح عملیات نبوده، از این رو کلمه کارآمدسازی به عنوان معادل پارسی برای Validation مطرح می گردد که مورد اقبال بسیاری مجامع فنی و تخصصی کشور نیز قرار گرفته است .

Yearly Impact:   مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Issue Info: 
  • Year: 

    2025
  • Volume: 

    31
  • Issue: 

    123
  • Pages: 

    57-81
Measures: 
  • Citations: 

    0
  • Views: 

    7
  • Downloads: 

    0
Abstract: 

Extended Abstract  Introduction and Objectives: In recent years, qualitative research has witnessed remarkable growth and increasing recognition among researchers across various disciplines, particularly within the humanities and social sciences. Alongside this growing interest, significant critiques and concerns have also emerged regarding the procedures, reliability, and credibility of qualitative methods. While validity and reliability have long held central importance in quantitative research, they are equally critical—albeit more challenging—to establish in qualitative inquiry.Given that qualitative research typically provides deeper, more meaningful insights than quantitative approaches, it inherently possesses greater potential to gain the trust of its audience. This makes the evaluation of qualitative research validity all the more essential. The present study aims to design a systematic and process-oriented model for evaluating the validity and reliability of qualitative research—referred to as the ConQual (Confidence in Qualitative Research) method.ConQual operates through a clear, structured framework beginning with a series of guiding questions used to assess the rigor of a qualitative study. The more precisely and comprehensively a study answers these questions, the higher its validity and reliability are considered to be. To demonstrate the practical implementation of this approach, the ConQual process was applied step-by-step to one form of meta-synthesis—meta-ethnography—thus allowing readers to better understand the operational logic of the ConQual method.Methodology: This study is grounded in the interpretivist paradigm, which views social phenomena as contextually situated and meaningful. Within this paradigm, the researcher seeks to understand and interpret meaningful social actions rather than to explain them through causal generalizations.The logic of this research is inductive, as it aims to infer a framework, pattern, or conceptual model from existing data. It follows a fundamental research orientation, seeking to generate a new evaluative model rather than to apply an existing one. The research is qualitative in nature, focusing on the understanding and interpretation of phenomena and their associated meanings.It employs a library-based approach, utilizing documented and credible sources—books, articles, and research reports. The purpose of this study is explanatory, aiming to identify and clarify the interrelations among the components of qualitative validation. Accordingly, its main strategy is documentary analysis, meaning that research data are derived from written and archival materials. The researchers prioritized consulting primary and recent sources to accurately delineate and operationalize the ConQual process, which was then demonstrated through its application in meta-ethnographic research.Results: ConQual provides a systematic framework for examining the factors that enhance or diminish the credibility of qualitative findings. Among the four key criteria commonly used to assess trustworthiness in qualitative research—dependability, transferability, credibility, and confirmability—this study focuses primarily on dependability and credibility.The evaluation process begins with a pre-ranking stage, classifying qualitative studies into four levels of rigor: strong, moderate, weak, and very weak. Studies demonstrating coherent design and methodological transparency are ranked higher, whereas those presenting only ideas or narratives without methodological grounding are placed in lower categories.After this preliminary classification, each study is assessed for dependability and credibility. Dependability is determined through a checklist of guiding questions examining the logical coherence between research objectives, processes, and results. Credibility, in the ConQual method, is evaluated by identifying the proportion of qualitative findings that fall within three interpretive levels: explicit, ambiguous, and unsupported.This process allows for an objective, stepwise appraisal of qualitative research trustworthiness, thereby introducing a replicable method for evaluating qualitative evidence.Discussion and Conclusion: The findings of this study underscore several key insights. First, there is a fundamental distinction between quantitative and qualitative research paradigms. Quantitative studies can often be evaluated using standardized techniques and computational methods with minimal researcher involvement. In contrast, qualitative research inherently relies on the deep engagement of the researcher with the phenomenon under study—its strength derives precisely from this involvement.Thus, qualitative inquiry should not be assessed merely through observable structures, metrics, or positivist criteria. The study highlights that the selection of appropriate validation tools in qualitative research—based on the nature of the data and research questions—can significantly enhance both the rigor and comprehensibility of findings, facilitating more effective implementation in practice.In quantitative research, validity and reliability are well-defined strengths; however, in qualitative research, they have often been perceived as areas of ambiguity and weakness. The present study seeks to address this gap by introducing a clear and structured validation process—ConQual—which offers a coherent approach for assessing and enhancing the credibility of qualitative studies.By systematizing the evaluation of qualitative findings, the ConQual method contributes to strengthening methodological transparency, fostering trust in qualitative research outcomes, and promoting a more balanced integration of qualitative approaches within the broader scientific community.

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Issue Info: 
  • Year: 

    2022
  • Volume: 

    12
  • Issue: 

    47
  • Pages: 

    75-93
Measures: 
  • Citations: 

    0
  • Views: 

    172
  • Downloads: 

    11
Abstract: 

Background: The expansion of the use of audio and video media technology has faced society with many medical, cultural and economic challenges. In the meantime, excessive use of mobile phones can cause many problems. Objective: The aim of this study was to construct and validate a questionnaire on physical and psychological injuries of mobile phones. Method: The method of the present study was descriptive-correlational and confirmatory factor analysis. The statistical population of the study consisted of all citizens of Khorramabad with a diploma or higher in 1399, which was selected as a statistical sample by available sampling method of 200 people online and virtual. Results: The results showed that the factorized physical and psychological harm questionnaire of cell phone with 42 questions and 10 components (fear of loss, vibration syndrome, duck syndrome, nomophobia, insomnia, hearing problem, eye syndrome, tunnel and neck syndrome SMS) and has good reliability, validity and flexibility in terms of psychometrics. Discussion and Conclusion: The questionnaire of factor analysis of physical and psychological injuries of mobile phones can be used to identify and study the physical and psychological injuries of mobile phones.

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Issue Info: 
  • Year: 

    2024
  • Volume: 

    10
  • Issue: 

    2
  • Pages: 

    11-22
Measures: 
  • Citations: 

    0
  • Views: 

    23
  • Downloads: 

    0
Abstract: 

High-performance liquid chromatography (HPLC) is recognized as a primary separation technique in modern pharmaceutical and biomedical analyses due to its exceptional efficiency and high sensitivity in detecting the analyte of interest. In the analysis of pharmaceutical samples, it is essential to ensure the reliability of the produced results. Method validation is a critical stage in the development of analytical methods, determining whether these methods are suitable and reliable for their intended purposes. The databases including PubMed, PubMed Central, Google Scholar, and ICHQ2R2 were searched using keywords such as HPLC, Validation, Accuracy, and Precision. To meet the requirements set by Good Manufacturing Practice (GMP) guidelines, pharmaceutical companies must establish a program to monitor and evaluate all their processes. The primary goal of this effort is to standardize all processes involved in the industry, including development, manufacturing, production, and analytical methods. This review article aims to provide insightful guidance on conducting validation for analytical methods that employed in pharmaceutical analysis. Specifically, it focuses on the validation process as per ICH Guidelines, which encompasses a comprehensive evaluation of performance characteristics such as accuracy, precision, specificity, linearity, working range, limit of detection, limit of quantification, robustness.

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Author(s): 

Issue Info: 
  • Year: 

    2022
  • Volume: 

    19
  • Issue: 

    1
  • Pages: 

    66-77
Measures: 
  • Citations: 

    1
  • Views: 

    11
  • Downloads: 

    0
Keywords: 
Abstract: 

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Author(s): 

Ozkan Sibel A.

Issue Info: 
  • Year: 

    2018
  • Volume: 

    24
  • Issue: 

    1
  • Pages: 

    1-2
Measures: 
  • Citations: 

    0
  • Views: 

    172
  • Downloads: 

    177
Keywords: 
Abstract: 

Analytical methods play significant role in many branches such as, food production, natural product analysis, environmental analysis, pharmaceutical and biomedical analysis, and life sciences, etc. In order to reach reliable, accurate and repeatable data validated analytical methods need to achieve this aim.....

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Author(s): 

ELLISON S.L.R. | WILLIAMS A.

Issue Info: 
  • Year: 

    1998
  • Volume: 

    3
  • Issue: 

    -
  • Pages: 

    6-10
Measures: 
  • Citations: 

    1
  • Views: 

    119
  • Downloads: 

    0
Keywords: 
Abstract: 

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View 119

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Author(s): 

قدیانی لیلا

Issue Info: 
  • Year: 

    1382
  • Volume: 

    3
  • Issue: 

    (ویژه نامه 10)
  • Pages: 

    56-56
Measures: 
  • Citations: 

    0
  • Views: 

    1658
  • Downloads: 

    0
Abstract: 

مقدمه و هدف: در این مقاله دو روش آموزشی تحت عناوین Case Study ,Case Method به عنوان تکنیکهای آموزشی مورد بررسی و نقد قرار گرفته و تفاوتها و شباهتهای هر کدام به طور جداگانه بررسی شده است و نکات کاربردی هر روش در آموزش پرستاری مورد بحث قرار گرفته است.مرور مطالعات: در این مقاله ابتدا تعاریف دو نوع متد آموزشی ارایه گردیده و سپس موارد استفاده از هر متد به طور جداگانه بحث شده است، و با توجه به ماهیت آموزش پرستاری ایران پیشنهادات کاربردی در این زمینه ارایه شده است. Case Method در گروههای آموزشی کوچکتر که مشاهدات ذهنی کمتری دارند و در ابتدای تجربه می باشند استفاده می شود. ولی Case Study در گروههای آموزشی بزرگتر که مشاهدات ذهنی بیشتری دارند و قدرت تجزیه و ترکیب و رشد بحث در آنها بیشتر می باشد استفاده می شود. از ویژگیهای مهم آنها می توان به افزایش قدرت تصمیم گیری افراد در موقعیتهای مختلف، لذتبخش تر کردن آموزش و علاقمند کردن به امر تدریس و ... نام برد.بحث و نتیجه گیری: با توجه به یافته های پژوهش و با توجه به محتوی برنامه های آموزشی پرستاری، محقق استفاده از روشهای Case Study ,Case Method را برای دانشجویان پرستاری توصیه می نماید. زیرا بهترین آموزش یادگیرنده ها زمانی مطرح می باشد که دانش هماهنگ و متنوع مهارتهای آموزشی با تجربیات در کنار هم می باشد.

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Issue Info: 
  • Year: 

    2024
  • Volume: 

    13
  • Issue: 

    25
  • Pages: 

    126-144
Measures: 
  • Citations: 

    0
  • Views: 

    19
  • Downloads: 

    0
Abstract: 

In this paper, an alternative approach in operational modal analysis is presented, utilizing image processing technique and transmissibility functions. Imaging sensors do not impose additional mass on the structure due to their non-contact nature, while transmissibility functions, independent of excitation type, can directly extract mode shapes. The innovation of this research lies in combining these two techniques to record dynamic responses and identify modal properties. To capture the temporal response history from video signals, the block-matching method with sub-pixel accuracy was employed. Validation was conducted by recording the response of the tip of a cantilevered steel beam subjected to impact excitation, using a high-speed camera and a laser vibrometer, simultaneously. The RMSE plots in the time domain and the PSD in the frequency domain indicate high accuracy of this method. Using this approach, the displacement time histories of various points on the structure were extracted from the video signals, and the modal properties, including natural frequencies, damping ratios, and mode shapes, were identified using the transmissibility matrix method. The results obtained from the proposed method were compared with the stochastic subspace identification (SSI) method and analytical solutions. The findings reveal the accuracy of the modal identification approach introduced in this article. The highest relative error in estimating the natural frequencies of the first and second modes, compared to the values from the laser method, are 0.19% and 0.13%, respectively, and in comparison to the analytical values, they are 0.34% and 1.5%, respectively.

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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